BDBM7266 14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,17}]octadeca-1(11),2,4,6,12(17),13,15-heptaen-9-one::9-bromopaullone::CHEMBL296586::Kenpaullone::NSC 664704::Paullone Analog 5::cid_3820

SMILES Brc1ccc2[nH]c-3c(CC(=O)Nc4ccccc-34)c2c1

InChI Key InChIKey=QQUXFYAWXPMDOE-UHFFFAOYSA-N

Data  3 KI  63 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 7266   

TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM7266(14-bromo-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  780nMAssay Description:Inhibition of human recombinant CDK2/cyclin A assessed as incorporation of [gamma-33P]-ATP into histone H1 substrate after 30 mins by scintillation c...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed